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教授风采
龚朝辉教授
2014-03-05 07:53     (点击: )

龚朝辉(Zhaohui GongPh.D.

 

职称(Academic Title

教授(Professor

 

研究领域Research Field

肿瘤分子生物学(Molecular Biology of Cancer

 

研究兴趣Research Interests

利用分子生物学、细胞生物学、实验动物学和生物信息学等技术研究:

1)非编码RNA在肿瘤发生、诊断和治疗中的作用(Noncoding RNAs in Tumorigenesis, Diagnosis and Treatment

2)非编码RNA自身调控和竞争性调控的分子机制(Self-regulations and Competitive regulations of Noncoding RNAs

 

教育背景Education Background

2001-2006年:浙江大学生物化学与分子生物学专业,博士(Ph.D., Biochemistry and Molecular Biology, Zhejiang University, Hangzhou, China

1997-2001年:浙江大学生物科学专业,学士(B.S., Biological Sciences, Zhejiang University, Hangzhou, China

 

工作经历Professional Experience

2013-至今:宁波大学医学院,教授(Professor, Ningbo University School of Medicine

2013年:美国德州大学MD安德森癌症中心,访问科学家(Visiting Scientist, The University of Texas MD Anderson Cancer Center, USA

2010年:美国肯塔基大学,访问学者(Visiting Scholar, University of Kentucky, USA

2007-2013年:宁波大学医学院,副教授(Associate Professor, Ningbo University School of Medicine

2006-2007年:宁波大学医学院,讲师(Assistant Professor, Ningbo University School of Medicine

 

执教课程(Teaching Courses

2010-至今:分子医学(Molecular Medicine

2007-至今:药物与健康(Drug and Health

2006-至今:高级分子生物学(Advanced Molecular Biology

2006-至今:生物化学与分子生物学(含实验),教育部双语教学示范课程(2008年),浙江省精品课程(2010年)(Biochemistry and Molecular Biology

 

学术兼职Committee and Broad Memberships

2014-至今:浙江省生物化学与分子生物学学会理事(Director, Zhejiang Society of Biochemistry and Molecular Biology

2014-至今:浙江省实验动物行业协会副理事长(Vice President, Zhejiang Society of Laboratory Animal

2014-至今:Journal of TumorISSN: 1819-6187Jacobs Journal of PulmonologyISSN: 2469-3170)编委(Editorial Member);Nature CommunicationsBMC Cancer等杂志审稿人(Reviewer

2012-至今:意大利卫生部、国家自然科学基金委、北京市科委、浙江省科技厅、山东省科技厅、黑龙江省科技厅、江西省科技厅等单位基金评审员(Reviewer

 

近期论文(Recent Publications)(*corresponding author

1.       Li J, Tian H, Yang J, Gong Z*. Long noncoding RNAs regulate cell growth, proliferation and apoptosis. DNA and Cell Biology 2016, 35(9), in press [Review]

2.       Yang J, Li J, Le Y, Zhou C, Zhang S, Gong Z*. PFKL/miR-128 axis regulates glycolysis by inhibiting AKT phosphorylation and predicts poor survival in lung cancer. American Journal of Cancer Research 2016, 6(2):473-485

3.       Yang L#, Yang J#, Li J, Shen X, Le Y, Zhou C, Wang S, Zhang S, Xu D, Gong Z*. MircoRNA-33a inhibits epithelial-to-mesenchymal transition and metastasis and could be a prognostic marker in non-small cell lung cancer. Scientific Reports 2015, 5:13677

4.       Jin G, Lee SW, Zhang X, Cai Z, Gao Y, Chou PC, Rezaeian AH, Han F, Wang CY, Yao JC, Gong Z, Chan CH, Huang CY, Tsai FJ, Tsai CH, Tu SH, Wu CH, Sarbassov DD, Ho YS, Lin HK*. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1. Molecular Cell 2015 58(6):989-1000

5.       Xu D, Li CF, Zhang X, Gong Z, Chan CH, Lee SW, Jin G, Rezaeian AH, Han F, Wang J, Yang WL, Feng ZZ, Chen W, Wu CY, Wang YJ, Chow LP, Zhu XF, Zeng YX, Lin HK*. Skp2-MacroH2A1-CDK8 axis orchestrates G2/M transition, polyploidy and tumorigenesis. Nature Communications 2015, 6: 6641

6.       Li J, Yang J, Zhou P, Le Y, Zhou C, Wang S, Xu D, Lin HK, Gong Z*. Circular RNAs in cancer: novel insights into origins, properties, functions and implications. American Journal of Cancer Research 2015, 5(2):472-480 [Review]

7.       Zhou P#, Wang Q#, Yang J, Li J, Guo J, Gong Z*. A statistical analysis of college biochemistry textbooks in China: the statuses on the publishing and usage. Eurasia Journal of Mathematics Science and Technology Education 2015, 11(3), 685-691

8.       Gong Z*. Pollution: Clear our skies over Beijing. Nature 2015, 517(7533):145 [Correspondence]

9.       Gong Z*, Yang J, Li J, Yang L, Le Y, Wang S, Lin HK. Novel insights into the role of microRNA in lung cancer resistance to treatment and targeted therapy. Current Cancer Drug Targets 2014, 14(3):241-258 [Review]

10.    Dong Z, Zhong Z, Yang L, Wang S, Gong Z*. MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9. Cancer Letters, 2014, 343(2):249-257

11.    Chen XQ*, Wang XB, Guan RF*, Tu J, Gong ZH*, Zheng N, Yang JH*, Zhang YY*, Ying MM*. Blood anticoagulation and antiplatelet activity of green tea (-)-epigallocatechin (EGC) in mice. Food &Function, 2013, 4(10):1521-1525

12.    Zhong Z, Dong Z, Yang L, Chen X, Gong Z*. MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells. Tumor Biology 2013, 34(3):1959-1965

13.    Zhong Z, Dong Z, Yang L, Gong Z*. miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer. Journal of Cancer Research and Clinical Oncology 2012, 138(10):1781-1788

14.    Zhong Z, Dong Z, Yang L, Chen X, Gong Z*. Inhibition of proliferation of human lung cancer cells by green tea catechins is mediated by upregulation of let-7. Experimental Therapeutic Medicine 2012, 4(2):267-272

15.    Pan L, Gong Z*, Zhong Z, Dong Z, Liu Q, Le Y, Guo J. Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells. Molecular and Cellular Biochemistry 2011, 335(1-2):257-263

16.    Gong Z*, Pan L, Le Y, Liu Q, Zhou M, Xing Z, Zhuo R, Wang S, Guo J. Glutamic acid decarboxylase epitope protects against autoimmune diabetes through activation of Th2 immune response and induction of possible regulatory mechanism. Vaccine 2010, 28(24):4052-4058

17.    Long XE, Gong ZH*, Pan L, Zhong ZW, Le YP, Liu Q, Guo JM, Zhong JC. Suppression of CDK2 expression by siRNAs induces cell cycle arrest and cell proliferation inhibition in human cancer cells. BMB reports 2010, 43(4):291-296

Full publications can be seen from PubMed:

http://www.ncbi.nlm.nih.gov/pubmed/?term=zhaohui+gong+or+zhao-hui+gong

 

部分获奖及荣誉(Selected Awards and Honors

2013年:浙江省高校中青年学科带头人(Distinguished Young and Middle-aged Academic Leaders at Zhejiang Universities, elected in Year 2013.

2012/2010年:宁波大学最受学生欢迎的青年教师 (The Most Popular Young Teachers for Students at Ningbo University, elected in Year 2012 and 2010).

2011年:宁波大学阳光教授 (Yangguang Professor at Ningbo University, elected in Year 2011).

2009年:浙江省新世纪151人才工程第三层次(Third Level of New Century 151 Talented Person Program in Zhejiang Province, elected in Year 2009

2007年:浙江省优秀青年教师资助计划(Outstanding Young Teachers in Zhejiang Province, elected in Year 2007

 

联系方式(Contact Information

地址/Add.: 浙江省宁波市江北区风华路818

邮编/P.C.: 315211

电话/Tel.: +86-574-87600740

传真/Fax: +86-574-87608638

电子邮箱/E-mail: gongzhaohui@nbu.edu.cn

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